Montgomery Lab
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PUBLICATIONS

Cialek C.A., Galindo G., Morisaki T., Zhao N., Montgomery T.A., and Stasevich T.J. (2022). Imaging translational control by Argonaute with single-molecule resolution in live cells. Nature Communications. 13(1):3345. Link

Montgomery B.E.*, Vijayasarathy T.*, Marks T.N., Cialek C.A., Reed K.J., and Montgomery T.A. (2021). 
Dual roles for piRNAs in promoting and preventing gene silencing in C. elegans. Cell Reports. 7, 110101. Link

Choi C.P., Tay R.J., Starostik M.R., Feng S., Moresco J.J., Montgomery B.E., Xu E., Hammonds M.A., Schatz M.C., Montgomery T.A., Yates J.R. 3rd, Jacobsen S.E., and Kim J.K. (2021). SNPC-1.3 is a sex-specific transcription factor that drives male piRNA expression in C. elegans. eLife 10:60681. Link

Reed, K.J. and Montgomery, T.A. (2020). Genes silenced down the generations, thanks to tails on messenger RNA. Nature 592, 191-192. Link

Manage, K.I., Rogers, A.K., Wallis, D.C., Uebel, C.J., Anderson, D.A., Nguyen, D.A.H., Arca, K., Brown, K.C., Rodrigues, R.J.C., de Albuquerque, B.F.M., Ketting, R.F., Montgomery, T.A., and Phillips, C.M. (2020). A Tudor domain protein, SIMR-1, promotes siRNA production at piRNA-targeted mRNAs in C. elegans. eLife 9:e56731. Link

Reed, K.J., Svendsen, J.M., Brown, K.C., Montgomery, B.E., Marks, T.N., Vijayasarathy, T., Parker, D.M., Osborne Nishimura, E., Updike, D.L., and Montgomery, T.A. (2020). Widespread roles for piRNAs and WAGO-class siRNAs in shaping the germline transcriptome of Caenorhabditis elegans. Nucleic Acids Research 48, 1811-1827. Link

Svendsen, J.M., Reed, K.J., Vijayasarathy, T., Montgomery, B.E., Tucci, R.M., Brown, K.C., Marks, T.N., Nguyen, D.A.H., Phillips, C.M., and Montgomery, T.A. (2019). henn-1/HEN1 Promotes Germline Immortality in Caenorhabditis elegans. Cell Reports 29, 3187-3199. Link

Brown, K.C. and Montgomery, T.A. (2018). The long and short of lifespan regulation by Argonautes. PLoS Genetics 14, e1007415. PDF

Svendsen, J.M. and Montgomery, T.A. (2018). piRNA rules of engagement. Developmental Cell 44, 657-658. PDF

Brown, K.C, Svendsen, J.M, Tucci, R.M, Montgomery, B.E., and Montgomery, T.A. (2017). ALG-5 is a miRNA-associated Argonaute required for proper developmental timing in the Caenorhabditis elegans germline. Nucleic Acids Research 45, 9093-9107. PDF

Weiser, N.E., Yang, D.X., Feng, S., Kalinava, N., Brown, K.C., Khanikar, J., Freeberg, M.A., Snyder, M.J., Csankovszki, G., Chan, R.C., Gu, S.G., Montgomery, T.A., Jacobsen, S.E., and Kim, J.K. (2017). MORC-1 integrates nuclear RNAi and transgenerational chromatin architecture to promote germline immortality. Developmental Cell 41, 408-423. PDF

Brown K.C. and Montgomery T.A. (2017). Transgenerational inheritance: perpetuating RNAi. Current Biology 27, R383-R385. PDF
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Phillips, C.M., Brown, K.C., Montgomery, B.E., Ruvkun, G., and Montgomery, T.A. (2015). piRNAs and piRNA-dependent siRNAs protect conserved and essential C. elegans genes from misrouting into the RNAi pathway. Developmental Cell 34, 457-465. PDF

Phillips, C.M., Montgomery, B.E., Breen, P.C., Roovers, E.F., Rim, Y.S., Ohsumi, T.K., Newman, M.A., van Wolfswinkel, J.C., Ketting, R.F., Ruvkun, G., and Montgomery, T.A. (2014). MUT-14 and SMUT-1 DEAD box RNA helicases have overlapping roles in germline RNAi and endogenous siRNA formation. Current Biology 24, 839-844. PDF

Montgomery, T.A. and Ruvkun, G. (2013). MicroRNAs visit the ER. Cell 153, 511-512. PDF

Shi, Z., Montgomery, T.A., Qi, Y., and Ruvkun, G. (2013). High-throughput sequencing reveals extraordinary fluidity of miRNA, piRNA and siRNA pathways in nematodes. Genome Research 23, 497-508. PDF

Carbonell, A., Fahlgren, N., Garcia-Ruiz, H., Gilbert, K.B., Montgomery, T.A., Nguyen, T., Cuperus, J.T., and Carrington, J.C. (2012).  Functional analysis of three Arabidopsis ARGONAUTES using slicer-defective mutants. Plant Cell 24, 3613-3629. PDF

Phillips, C.M., Montgomery, T.A., Breen, P.C., and Ruvkun, G. (2012). MUT-16 promotes formation of perinuclear Mutator foci required for RNA silencing in the C. elegans germline. Genes & Development 26,1433-1444. PDF

Montgomery, T.A., Rim, Y.S., Zhang, C., Dowen, R.H., Phillips, C.M., Fischer, S.E., and Ruvkun, G. (2012). PIWI associated siRNAs and piRNAs specifically require the Caenorhabditis elegans HEN1 ortholog henn-1. PLoS Genetics 8, e1002616. PDF

Zhang, C., Montgomery, T.A., Fischer, S.E., Garcia, M.D.A., Riedel, C.G., Fahlgren, N., Sullivan, C.M., Carrington, J.C., and Ruvkun, G. (2012). The Caenorhabditis elegans RDE-10/RDE-11 complex regulates RNAi by promoting secondary siRNA amplification. Current Biology 22, 881-890. PDF

Fischer, S.E., Montgomery, T.A., Zhang, C., Fahlgren, N., Breen, P.C., Hwang, A., Sullivan, C.M., Carrington, J.C., and Ruvkun, G. (2011). The ERI-6/7 helicase acts at the first stage of an siRNA amplification pathway that targets recent gene duplications. PLoS Genetics 7, e1002369. PDF

Zhang, C.*, Montgomery, T.A.*, Gabel, H.W.*, Fischer, S.E., Phillips, C.M., Fahlgren, N., Sullivan, C.M., Carrington, J.C., and Ruvkun, G. (2011). mut-16 and other mutator class genes modulate 22G and 26G siRNA pathways in Caenorhabditis elegans. PNAS 108, 1201-1208. PDF

Cuperus, J.T.*, Carbonell, A.*, Fahlgren, N., Garcia-Ruiz, H., Burke, R.T., Takeda, A., Sullivan, C.M., Gilbert, S.D., Montgomery, T.A., and Carrington, J.C. (2010). Unique functionality of 22-nt miRNAs in triggering RDR6-dependent siRNA biogenesis from target transcripts in Arabidopsis. Nature Structural and Molecular Biology 17, 997-1003.  PDF

​Cuperus, J.T., Montgomery, T.A., Fahlgren, N., Burke, R.T., Townsend, T., Sullivan, C.M., and Carrington, J.C. (2010). Identification of MIR390a precursor processing-defective mutants in Arabidopsis by direct genome sequencing. PNAS 107, 466-471. PDF

Chitwood, D.H., Nogueira, F.T., Howell, M.D., Montgomery, T.A., Carrington, J.C., and Timmermans, M.C. (2009). Pattern formation via small RNA mobility. Genes & Development 23, 549-554. PDF

Fahlgren, N., Sullivan, C.M., Kasschau, K.D., Chapman, E.J., Cumbie, J.S., Montgomery, T.A., Gilbert, S.D., Dasenko, M., Backman, T.W., Givan, S.A., and Carrington, J.C. (2009). Computational and analytical framework for small RNA profiling by high-throughput sequencing. RNA 15, 992-1002. PDF

​Montgomery, T.A., Yoo, S.J., Fahlgren, N., Gilbert, S.D., Howell, M.D., Sullivan, C.M., Alexander, A., Nguyen, G., Allen, E., Ahn, J.H., and Carrington, J.C.  (2008). AGO1-miR173 complex initiates phased siRNA formation in plants. PNAS 105, 20055-20062. PDF

Montgomery, T.A. and Carrington, J.C. (2008). Splicing and dicing with a SERRATEd edge. PNAS 105, 8489-8490. PDF

Montgomery, T.A., Howell, M.D., Cuperus, J.T., Li, D., Hansen, J.E., Alexander, A.L., Chapman, E.J., Fahlgren, N., Allen, E., and Carrington, J.C. (2008). Specificity of ARGONAUTE7-miR390 interaction and dual functionality in TAS3 trans-acting siRNA formation. Cell 133, 128-141. PDF

Liu, P.P., Montgomery, T.A., Fahlgren, N., Kasschau, K.D., Nonogaki, H., and Carrington, J.C. (2007). Repression of AUXIN RESPONSE FACTOR10 by microRNA160 is critical for seed germination and post-germination stages. Plant Journal 52, 133-146. PDF

Fahlgren, N.*, Montgomery, T.A.*, Howell, M.D.*, Allen, E., Dvorak, S.K., Alexander, A.L., and Carrington, J.C. (2006). Regulation of AUXIN RESPONSE FACTOR3 by TAS3 ta-siRNA affects developmental timing and patterning in Arabidopsis. Current Biology 16, 939-944. PDF
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